By George Klein, Sidney Weinhouse, Alexander Haddow (Eds.)
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Extra resources for Advances in Cancer Research, Vol. 13
1. A complete feline leukemia virus particle in an extracellular space, showing the internal, intermediate, and out,er membranes and projections from the surface. Magnification : X 180,000. of spontaneous and induced cases, which was isolated by sedimentation to equilibrium in sucrose gradients. /ml. 2. A feline leukemia virus particle budding from the surface of a lymphoid cell in the bone marrow of an infected kitten. Magnification: XlS0,OOO. which can be classified with the leukemia viruses of the mouse and fowl.
I n the ensuing graft-versus-host reaction the tumor as well as t,he normal cells of the host sustain damage and good antitumor effect is, therefore, often associated with severe side effects. , 1967). Reports conflict whether allogeneic cells from unimmunized donors (Math&,1966) or from donors immunized with the tumor to be treated (Woodruff and Symes, 1962; Woodruff and Boak, 1965) are more effective. 3. When specifically immune lymphoid cells from donors which can be syngeneic, allogeneic, or heterogeneic and injected into tumor-bearing IMMUNOBLASTS I N RESISTANCE TO CANCER 31 animals that have not been specifically immunosuppressed, the injected cells do not proliferate and there is no graft-versus-host reaction.
Cancer &en. 28, 1577-1585. Fisher. E.. , and Fisher, €3. (1969). Nature 221, 287-288. Gorer, P. A. (1961). Advan. Immunol. 1, 345393. Gorer, P. A,, and Amos, D. B. (1956). Cancer Res. 16, 338-343. Gowans, J. L. (1957). Brit. J . Ezpptl. Pathol. 38, 67-78. Gowans, J. L. (1959). J . Physiol. (London) 146, 54-69. Gowans. J. , and Knight, E. J. (1964). Proc. Roy. Soc. (London) B159, 257-282. Gowans. J. L.. and Uhr. J. N’. (1966). J . Ezptl. Me& 124, 1017-1030. 36 P. ALEXANDER AND J. G . HALL 0 Granger, G.
Advances in Cancer Research, Vol. 13 by George Klein, Sidney Weinhouse, Alexander Haddow (Eds.)