George Klein, Sidney Weinhouse (Eds.)'s Advances in Cancer Research, Vol. 28 PDF

By George Klein, Sidney Weinhouse (Eds.)

ISBN-10: 0120066289

ISBN-13: 9780120066285

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Additional info for Advances in Cancer Research, Vol. 28

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M. BURNET From another angle, I am attracted to Holley’s (1972) hypothesis of the nature of malignant growth. From one point of view, cell growth in the body is determined by the concentration inside the cell of one or more low molecular weight nutrients as controlled by transport mechanisms in the cell surface. According to need or under hormonal stimulation these allow selective entry of nutrients from the standard circulating mixture. Cancer then arises by any appropriate genetic (or paragenetic) breakdown in one of these mechanisms.

The incidence of bronchial carcinoma in women (10%)was slightly higher than in the general population (6%), but this may be an artifact because of the small number of patients involved. The common types of neoplasms seen in the general population usually occur in the older age groups, and this may, perhaps, account for their paucity in the transplant patients who are a relatively young group. 1. Solid Lymphomas Recent advances in immunology and immunopathology have resulted in attempts to reclassify the lymphomas (Lukes and Collins, TUMORS ARISING IN ORGAN TRANSPLANT RECIPIENTS 41 1974; Whiteside and Rowlands, 1977).

28 F. M. BURNET Kirby, D. R. , and Cowell, T. P. (1968). In “Epithelial-Mesenchymal Interactions” (R. Fleischmajer and R. E. ), pp. 64-77. Williams & Wilkins, Baltimore, Maryland. , Sjogren, H. , and Hellstrom, K. E. Cancer Res. 20, 15611572. , Swenberg, J. Am. /. Pathol. 63, 37-56. Lancaster, H. , and Nelson, J. Med. J . Aust. 1, 452-456. Lancet annotation. Lancet 2, 651. Lehmann, A. , Arlett, C. , Paterson, M. , Lohman, P. H. , de Weerd-Kastelein, E. , and Bootsma, D. Proc. Natl. Acad. Sci. A.

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Advances in Cancer Research, Vol. 28 by George Klein, Sidney Weinhouse (Eds.)

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