By George F. Vande Woude
Advances in melanoma examine presents helpful info at the interesting and fast-moving box of melanoma examine. right here, once more, striking and unique experiences are provided on a number of themes, together with liposome-based chemotherapy and immunotherapy, human polyomaviruses, the function of micro RNAs in CLL, and melanoma and ldl cholesterol.
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Additional info for Advances in Cancer Research, Volume 106
2004). , 1996). , 2005). , 1999). Thus, ST in a concerted manner targets the cyclin-dependent kinases involved in G1–S phase transition. , 2001). , 2004). Many genes are altered in expression via ST interaction with PP2A, but several other alterations are in fact independent of ST binding to PP2A, thus demonstrating that other functions of ST exist, although at the moment other cellular targets have not been identified. C. , 2005; Saenz Robles and Pipas, 2009). Dependent on the cell system, LT alone, or in conjunction with ST, can induce either no stimulation of proliferation, hyperplasia, dysplasia, carcinoma, or a fullblown metastatic phenotype.
SV40 17KT antigen complements dnaj mutations in large T antigen to restore transformation of primary human fibroblasts. Virology 315, 148–158. , and zur Hausen, H. (1981). B-lymphotropic papovavirus and possibility of infections in humans. J. Med. Virol. 6, 301–308. Brinster, R. , Chen, H. , Levine, A. , and Palmiter, R. D. (1984). Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 37, 367–379. , and Rotter, V. (2009). When mutants gain new powers: news from the mutant p53 field.
And Gattuso, P. (2009). Update on human polyomavirus BK nephropathy. Diagn. Cytopathol. 37, 773–779. , Lock, R. , Williams, G. , Golemis, E. , Roberts, T. , Jat, P. , and Gjoerup, O. V. (2004). Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1. Proc. Natl. Acad. Sci. USA 101, 947–952. Counter, C. , Hahn, W. , Caddle, S. , Beijersbergen, R. , Lansdorp, P. , Sedivy, J. , and Weinberg, R. A. (1998). Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.
Advances in Cancer Research, Volume 106 by George F. Vande Woude